Advanced Imaging, Better Biopsy, Smarter Treatment, Fewer Side Effects - Transperineal MRI-Guided Prostate Biopsies avoids risks associated with the conventional trans-rectal approach.
Many men are advised to be screened annually or every other year for prostate cancer. Screening may consist of a blood test, prostate-specific antigen (PSA) and digital rectal exam (DRE). If the patient has a confirmed elevated or rising PSA, or an abnormal DRE, the next step is often to proceed with a prostate biopsy.
The overwhelming majority of prostate biopsies are conducted trans-rectally. This approach unfortunately brings several risks – Infections continue to be the greatest risk associated with trans-rectal prostate biopsies; the risk of sepsis, a severe life-threatening infection, is approximately 1 to 2 in 100. In addition, some areas of the prostate, including the anterior prostate, are under-sampled with a systematic trans-rectal approach, which means that some clinically significant prostate cancers may be missed. Both of these problems can be addressed by performing the prostate biopsy via a transperineal approach.
In transperineal biopsy, the urologist passes the biopsy needle through the perineal skin and into the prostate, rather than passing the biopsy needle through a potentially contaminated rectum. The biopsy needle is still guided by an ultrasound placed in the rectum. This approach lowers the risk of sepsis to 1 in 500, rather than the approximate 1 to 2 in 100 risk of sepsis related to trans-rectal biopsy.
Transperineal biopsy is appropriate for all patients, but may specifically benefit patients with the following conditions:
Studies show a higher detection rate with the transperineal approach. The main benefit is safety, due to the lower risk of severe life-threatening infection. Also, with a transperineal approach it is much easier to access the anterior prostate, which is not well sampled with trans-rectal biopsy.
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